111, Inc. Announces First Quarter 2021 Unaudited Financial Results

SHANGHAI,May 19,2021 -- 111,Inc. ("111" or the "Company") (NASDAQ: YI),a leading tech-enabled healthcare platform company committed to digitally connecting patients with medicine and healthcare services in China,today announced its unaudited financial results for the first quarter ended March 31,2021.

First Quarter 2021 Highlights

Net revenues were RMB2.6 billion (US$396.0 million),representing an increase of 64.7% year-over-year. Revenue growth was 89.0% excluding pandemic-related items(1).

Operating expenses(2) were RMB289.0 million (US$44.1 million),representing an increase of 43.6% year-over-year. Operating expenses accounted for 11.1% of net revenue this quarter as compared to 12.8% in the same quarter of last year.

Non-GAAP net loss attributable to ordinary shareholder(3) was RMB109.3 million (US$16.7 million),compared to RMB109.4 million in the same quarter of last year. As a percentage of net revenues,non-GAAP net loss attributable to ordinary shareholders decreased to 4.2% this quarter from 6.9% in the same quarter of last year.

Cash and cash equivalents,restricted cash and short-term investments amounted to RMB 1.2 billion (US$177.5 million) as of March 31,2021.

(1) Pandemic-related items consist of masks,protective clothing and medicine for fever which have an occasional revenue increase in the first quarter of 2020 due to the breakout of COVID-19.

(2) Operating expense consists of fulfillment expenses,selling and marketing expenses,general and administrative expenses,technology expenses and other operating expenses.

(3)Non-GAAP net loss attributable to ordinary shareholders represents net loss attributable to ordinary shareholders excluding share-based compensation expenses.

"We delivered another strong quarter of growth in Q1 2021,with net revenue of RMB2.6 billion. This was achieved despite the typical seasonal retail lull caused by the Lunar New Year,as well as the unusually strong first quarter we had in 2020,driven by high demand for pandemic-related products due to COVID-19," said Mr. Junling Liu,Co-Founder,Chairman,and Chief Executive Officer of 111.

"As part of our commitment to advancing China's healthcare system,we continue to build upon our transformative,cutting-edge technology and S2B2C model to provide enterprise solutions to enable healthcare businesses better serve their consumers. Our top line growth is driven by our S2B2C model,and is a testament of the tremendous progress in our mission to digitally connect patients with medicine and healthcare services."

Mr. Liu added,"To briefly highlight our S2B2C model,the 'S' is our innovative supply-chain platform that encompasses industry-leading technology behind the platform and our network of suppliers,such as pharmaceutical companies,distributors and other service providers. This 'S' is digitally connected to the 'B,' our rapidly expanding network of pharmacies,doctors,clinics,and other healthcare businesses. The platform works in harmony as doctors can utilize our Cloud Pharmacy,Cloud Clinic,and various doctor-patient platforms to provide online consultations,e-prescription services,and follow-up care to patients. As a result,our transformative S2B2C model delivers better doctor-patient experiences and more positive care outcomes."

"This quarter demonstrated the solid progress we have made in additional partnerships with pharmaceutical companies and healthcare providers. 111's innovative approach to product commercialization makes us a valuable partner to pharmaceutical companies as these partnerships offer access to access to our vast network of pharmacies and doctors,which creates a streamlined approach to launching new products. Further,our commercialization platform allows pharmaceutical companies to sell their products outside of the hospital system,through both online and offline channels. This enables pharmaceutical companies to launch their products as soon as they are approved,giving patients accelerated access to much-needed medication. As of March 31,we have developed over 360 direct partnerships with pharmaceutical companies."

"To further strengthen our supply chain platform,the two additional new fulfillment centers in Northwest and Northeast China that we announced in March are now fully operational and we are also expanding some of our existing fulfillment centers to meet growing demand for our services. In the meantime,our supply chain platform is further strengthened by more and more market place vendors. Currently there are over 900 marketplace vendors utilizing our platform to expand their geographical reach."

"As we advance our S2B2C model,we are making progress in our Supply Chain Platform to Pharmacy to Consumer ("S2P2C") offering,via which we leverage our scale to provide over 340,000 pharmacies with a wide selection of products and services. These services allow pharmacies to elevate their businesses through cutting-edge technology,such as cloud-based systems that manage inventory,product selection,and pricing. We also provide powerful digital solutions that helps pharmacies improve their customer experience,as well as the tools and support necessary to enable previously offline businesses establish a significant presence online."

"Concurrent with the growth of our S2B2C and S2P2C segments,we are also expanding the reach of our Supply Chain Platform to Doctors to Consumer ("S2D2C") business," commented Mr. Liu. "Our industry-leading technology is transforming and modernizing the traditional in-person medical care process by offering telehealth and patient management tools. These tools allow for convenient and timely medical care ranging from diagnostics to treatment,as well as follow-up and routine care. Our combination of cutting-edge technology and a robust network of doctors puts 111 at the forefront of the healthcare industry's new era of Internet + Medical Care + Medicine."

"Finally,this foundation of our model is extended to the 'C',the consumer or patient,who is digitally connected to doctors,medicine,and other healthcare providers and services. Consumers can leverage a wide network of doctors and pharmacies that were previously out-of-reach or unknown. We believe that the benefits to having this integrated digital platform is clear – improved access to healthcare and better patient outcomes. As a result,our omni-channel,digital platform fills many gaps in the traditional healthcare ecosystem."

"Given the industry tailwind and the leadership position 111 has established in our space,we continue to make significant investments in our team,technology,and supply chain platform. As a testament to our confidence in driving more business momentum,we have more than doubled the size of our technology team over the past 12 months,and have made significant investment in our patient management portals and other technology offerings. In addition,we continue to add to the pharmaceuticals and doctors support team that we began building last year,consisting of professionals with expertise in specific disease areas such as endocrinology,oncology,neurology,and others."

"In conclusion," said Mr. Liu,"As we move forward,we will continue to leverage the immense market opportunities in the digitization and transformation of healthcare in China. Our mission is to digitally connect patients with medicine and healthcare products and services. By bridging the patient access gap,our platform also ensures a win-win scenario for all parties in the healthcare ecosystem. Whether it is through our established S2B2C model,or our rapidly expanding S2P2C and S2D2C offerings,patients,pharmacies and pharmaceutical companies all benefit. Reflective of our strong Q1 2021 performance,111 is in an excellent position to continue to transform the healthcare industry in China."

First Quarter 2021 Financial Results

Net revenueswereRMB2.6 billion(US$396.0 million),representing an increase of 64.7% fromRMB1.6 billionin the same quarter of last year.

As of March 31,2021,the Group had two reporting segments,Business to Business ("B2B") and Business to Consumer ("B2C"). Revenue contribution from the Company's E-Channel was previously disclosed as a separate segment,but has been incorporated in the B2B segment since the third quarter of 2020. The Company revised prior comparative periods to conform to the current period segment presentation as follows:

(In thousands RMB)

For the three months ended March 31,

2020

2021

YoY

B2B Net Revenue

Product...............................................................................................

1,378,450

2,440,504

77.0%

Service...............................................................................................

2,517

12,025

377.8%

Sub-Total............................................................................................

1,380,967

2,452,529

77.6%

Cost of Products Sold(4).....................................................................

1,335,869

2,364,354

77.0%

Segment Profit..................................................................................

45,098

88,175

95.5%

Segment Profit %..............................................................................

3.3%

3.6%

(In thousands RMB)

For the three months ended March 31,

2020

2021

YoY

B2C Net Revenue

Product................................................................................................

190,684

137,150

(28.1%)

Service................................................................................................

4,017

5,063

26.0%

Sub-Total............................................................................................

194,701

142,213

(27.0%)

Cost of Products Sold[4]......................................................................

152,201

114,618

(24.7%)

Segment Profit..................................................................................

42,500

27,595

(35.1%)

Segment Profit %..............................................................................

21.8%

19.4%

(4) For segment reporting purposes,purchase rebate is allocated to B2B segment and B2C segment primarily based on the amount of cost of products sold for each segment. Cost of products sold does not include other direct costs related to cost of product sales such as shipping and handling expense,payroll and benefits of logistic staff,logistic centers rental expenses and depreciation expenses,which are recorded in the fulfillment expenses.

Operating costs and expenseswereRMB2.8 billion(US$422.5 million),representing an increase of 63.8% fromRMB1.7 billionin the same quarter of last year.

Cost of products soldwasRMB2.5 billion(US$378.4 million),representing an increase of 66.6% fromRMB1.5 billionin the same quarter of last year. The increase was primarily due to our rapid revenue growth in B2B business,which increased by 77.6% as compared to the same quarter last year.

Fulfillment expenseswereRMB66.3 million(US$10.1 million),representing an increase of 19.2% fromRMB55.6 millionin the same quarter of last year. Fulfillment expenses accounted for 2.6% of net revenues this quarter as compared to 3.5% in the same quarter of last year.

Selling and marketing expenseswereRMB122.4 million(US$18.7 million),representing an increase of 27.9% fromRMB95.8 millionin the same quarter of last year,mainly due to increase in the number of sales staffs and expenses associated with the expansion of the S2B2C business. As a percentage of net revenues,selling and marketing expense further reduced to 4.7% in the quarter from 6.1% in the same quarter of last year.

General and administrative expenseswereRMB52.1 million(US$8.0 million),representing an increase of 75.8% fromRMB29.7 millionin the same quarter of last year. As a percentage of net revenues,general and administrative expense increased to 2.0% in the quarter from 1.9% in the same quarter of last year.

Technology expenseswereRMB49.7 million(US$7.6 million),representing an increase of 136.2% fromRMB21.0 millionin the same quarter of last year,mainly due to our increased investments in technology. Technology expenses accounted for 1.9% of net revenues this quarter as compared to 1.3% in the same quarter of last year.

Loss from operationswasRMB173.3 million(US26.4 million),compared toRMB113.7 millionin the same quarter of last year. As a percentage of net revenues,loss from operations decreased to 6.7% in the quarter from 7.2% in same quarter of last year.

Non-GAAP loss from operations(5)wasRMB135.9million(US$20.7 million),compared toRMB98.5 millionin the same quarter of last year. As a percentage of net revenues,non-GAAP loss from operations decreased to 5.2% in the quarter from 6.3% in same quarter of last year.

Net loss attributable to ordinary shareholderswasRMB146.6million(US$22.4 million),compared toRMB124.6 millionin the same quarter of last year. As a percentage of net revenues,net loss attributable to ordinary shareholders decreased to 5.7% in the quarter from 7.9% in same quarter of last year.

Non-GAAP net loss attributable to ordinary shareholders wasRMB109.3 million(US$16.7 million),compared toRMB109.4 millionin the same quarter of last year. As a percentage of net revenues,non-GAAP net loss attributable to ordinary shareholders decreased to 4.2% in the quarter from 6.9% in same quarter of last year.

Lossper ADSwasRMB1.78(US$0.28),compared toRMB1.52for the same quarter of last year.

Non-GAAP lossper ADS(6)wasRMB1.33(US$0.21),compared toRMB1.34for the same quarter of last year.

As ofMarch 31,the Company hadcash and cash equivalents,restricted cashand short-term investmentsofRMB 1.2 billion (US$177.5 million),compared toRMB1.6 billionas ofDecember 31,2020.

[5] Non-GAAP loss from operations represents loss from operations excluding share-based compensation expenses.

[6] Non-GAAP loss per ADS represents loss per ADS excluding share-based compensation expenses per ADS.

Business Outlook

For the second quarter of 2021,the Company expects its total net revenues to be between RMB2.92 billion and RMB3.08 billion,representing a year-over-year growth of approximately 80% to 90%.

The above outlook is based on the current market conditions and reflects the Company's current and preliminary estimates of market and operating conditions and customer demand,which are all subject to changes.

Conference Call

111's management team will host an earnings conference call today,Wednesday,2020,at 7:30 AM U.S. Eastern Time (7:30 PM Beijing Time on the same day).

Details for the conference call are as follows:

Event Title:

111,Inc. First Quarter 2021 Earnings Conference Call

Registration Link:

http://apac.directeventreg.com/registration/event/5638569

All participants must use the link provided above to complete the online registration process in advance of the conference call. Upon registering,each participant will receive a set of participant dial-in numbers,the Direct Event passcode,and a unique Registration ID,which can be used to join the conference call.

Please dial in 15 minutes before the call is scheduled to begin and provide the Direct Event passcode and unique Registration ID you have received upon registering to join the call.

A telephone replay of the call will be available after the conclusion of the conference call until May 27,9:59 A.M. ET on:

United States:

+1-855-452-5696

International:

+61-2-8199-0299

Conference ID:

5638569

A live and archived webcast of the conference call will be available on the Investor Relations section of 111's website at http://ir.111.com.cn/.

Use of Non-GAAP Financial Measures

In evaluating the business,the Company considers and uses non-GAAP loss from operations,non-GAAP net loss attributable to ordinary shareholders,and non-GAAP loss per ADS,non-GAAP measures,as supplemental measures to review and assess its operating performance. The Company defines non-GAAP loss from operations as loss from operations excluding share-based compensation expenses. The Company defines non-GAAP net loss attributable to ordinary shareholders as net loss attributable to ordinary shareholders excluding share-based compensation expenses. The Company defines non-GAAP loss per ADS as loss per ADS excluding share-based compensation expenses per ADS. The presentation of these non-GAAP financial measures is not intended to be considered in isolation or as a substitute for the financial information prepared and presented in accordance with U.S. GAAP.

The Company believes that non-GAAP loss from operations,and non-GAAP loss per ADS help identify underlying trends in its business that could otherwise be distorted by the effect of certain expenses that it includes in loss from operations and net loss. Share-based compensation expenses is a non-cash expense that varies from period to period. As a result,management excludes the items from its internal operating forecasts and models. Management believes that the adjustments for share-based compensation expenses provide investors with a reasonable basis to measure the company's core operating performance,in a more meaningful comparison with the performance of other companies. The Company believes that non-GAAP loss from operations,and non-GAAP loss per ADS provide useful information about its operating results,enhances the overall understanding of its past performance and future prospects and allow for greater visibility with respect to key metrics used by the management in their financial and operational decision-making.

The non-GAAP financial measures are not defined under U.S. GAAP and are not presented in accordance with U.S. GAAP. The non-GAAP financial measures have limitations as analytical tools. One of the key limitations of using non-GAAP loss from operations,or non-GAAP loss per ADS is that it does not reflect all items of income and expense that affect the Company's operations. Further,the non-GAAP financial measures may differ from the non-GAAP information used by other companies,including peer companies,and therefore their comparability may be limited.

The Company compensates for these limitations by reconciling the non-GAAP financial measures to the most comparable U.S. GAAP measures,all of which should be considered when evaluating the Company's performance. The Company encourages you to review its financial information in its entirety and not rely on a single financial measure.

Reconciliation of the non-GAAP financial measures to the most comparable U.S. GAAP measures is included at the end of this press release.

Exchange Rate Information Statement

This announcement contains translations of certain RMB amounts into U.S. dollars at specified rates solely for the convenience of the reader. Unless otherwise noted,all translations from RMB to U.S. dollars are made at a rate of RMB6.5518 to US$1.00,the exchange rate set forth in the H.10 statistical release of the Board of Governors of the Federal Reserve System as of March 31,2021.

Forward-Looking Statements

This press release contains forward-looking statements. These statements constitute "forward-looking" statements within the meaning of Section 21E of the Securities Exchange Act of 1934,as amended,and as defined in the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates," "target," "confident" and similar statements. Among other things,the Business Outlook and quotations from management in this announcement,as well as 111's strategic and operational plans,contain forward-looking statements. 111 may also make written or oral forward-looking statements in its periodic reports to the U.S. Securities and Exchange Commission,in its annual report to shareholders,in press releases and other written materials and in oral statements made by its officers,directors or employees to third parties. Such statements are based upon management's current expectations and current market and operating conditions and relate to events that involve known or unknown risks,uncertainties and other factors,all of which are difficult to predict and many of which are beyond the Company's control. Forward-looking statements involve inherent risks,uncertainties and other factors that could cause actual results to differ materially from those contained in any such statements. Potential risks and uncertainties include,but are not limited to,uncertainties as to the Company's ability comply with extensive and evolving regulatory requirements,its ability to compete effectively in the evolving PRC general health and wellness market,its ability to manage the growth of its business and expansion plans,its ability to achieve or maintain profitability in the future,its ability to control the risks associated with its pharmaceutical retail and wholesale businesses,and the Company's ability to meet the standards necessary to maintain listing of its ADSs on the Nasdaq Global Market,including its ability to cure any non-compliance with Nasdaq's continued listing criteria. Further information regarding these and other risks,uncertainties or factors is included in the Company's filings with the U.S. Securities and Exchange Commission. All information provided in this press release is as of the date of this press release,and 111 does not undertake any obligation to update any forward-looking statement as a result of new information,future events or otherwise,except as required under applicable law.

About 111,Inc.

111,Inc. (NASDAQ: YI) ("111" or the "Company") is a leading tech-enabled healthcare platform company committed to digitally connecting patients with medicine and healthcare services in China. The Company provides consumers with better access to pharmaceutical products and healthcare services directly through its online retail pharmacy,1 Pharmacy,and indirectly through its offline virtual pharmacy network. The Company also offers online healthcare services through its internet hospital,1 Clinic,which provides consumers with cost-effective and convenient online consultation,electronic prescription service,and patient management service. In addition,the Company's online platform,1 Medicine Marketplace,serves as a one-stop shop for pharmacies to source a vast selection of pharmaceutical products. With the largest virtual pharmacy network in China,111 enables offline pharmacies to better serve their customers with cloud-based services. 111 also provides an omni-channel drug commercialization platform to its strategic partners,which includes services such as digital marketing,patient education,data analytics,and pricing monitoring.

For more information on 111,please visit: http://ir.111.com.cn/.

For more information,please contact:

111,Inc.

Investor Relations

Stephen Kilmer

Phone: +1 646-274-3580

Email: stephen@kilmerlucas.com

111,Inc.

Media Relations

Email: ir@111.com.cn

Phone: +86-021-2053 6666 (China)

111,Inc.

UNAUDITED CONDENSED CONSOLIDATED BALANCE SHEETS

(In thousands,except for share and per share data)

As of

As of

December 31,2020

March 31,2021

RMB

RMB

US$

ASSETS

Current Assets:

Cash and cash equivalents

1,189,620

822,287

125,505

Restricted cash

128,914

140,689

21,473

Short-term investments

300,167

200,084

30,539

Accounts receivable,net

163,094

212,783

32,476

Note Receivable

12,583

54,365

8,298

Inventories

766,529

1,032,317

157,562

Prepayments and other current assets

311,797

365,535

55,792

Total current assets

2,872,704

2,828,060

431,645

Property and equipment

43,439

55,312

8,442

Intangible assets

6,517

6,198

946

Long-term investments

140

140

21

Other non-current assets

5,061

10,485

1,600

Operating lease right-of-use asset

98,628

179,125

27,340

Total Assets

3,026,489

3,079,320

469,994

LIABILITIES AND EQUITY

Current liabilities including amounts of the consolidated

VIE without recourse to the Company

Short-term borrowings

229,250

44,850

6,845

Accounts payable

1,073,352

1,372,734

209,520

Accrued expense and other current liabilities

327,118

330,016

50,370

Total Current liabilities

1,629,720

1,747,600

266,735

Long-term operating lease liabilities

62,388

126,792

19,352

Other non-current liabilities

3,736

3,186

486

Total Liabilities

1,695,844

1,877,578

286,573

Mezzanine Equity

Redeemable non-controlling interests

924,245

908,915

138,728

Shareholders' Equity

Ordinary shares Class A

30

30

4

Ordinary shares Class B

25

25

4

Treasury shares

(34,972)

(34,972)

(5,338)

Additional paid-in capital

2,669,279

2,708,237

413,357

Accumulated deficit

(2,339,868)

(2,486,508)

(379,515)

Accumulated other comprehensive income

62,911

64,533

9,850

Total shareholders' equity

357,405

251,345

38,362

Non-controlling interest

48,995

41,482

6,331

Total equity

406,400

292,827

44,693

Total liabilities,mezzanine equity and equity

3,994

111,Inc.

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS

(In thousands,except for share,per share and per ADS data)

For the three months ended March 31

2020

2021

RMB

RMB

US$

Net revenues

1,575,668

2,594,742

396,035

Operating costs and expenses:

Cost of product sold

(1,488,070)

(2,478,972)

(378,365)

Fulfillment expenses

(55,603)

(66,255)

(10,112)

Selling and marketing expenses

(95,751)

(122,428)

(18,686)

General and administrative expenses

(29,656)

(52,137)

(7,958)

Technology expenses

(21,037)

(49,698)

(7,585)

Other operating (expenses) income,net

754

1,483

226

Total operating costs and expenses

(1,689,363)

(2,768,007)

(422,480)

Loss from operations

(113,695)

(173,265)

(26,445)

Interest income

288

3,115

475

Interest expense

(1,604)

(1,813)

(277)

Foreign exchange loss

(10,996)

(511)

(78)

Other income,net

548

2,991

457

Loss before income taxes

(125,459)

(169,483)

(25,868)

Income tax expense

-

-

-

Net loss

(125,868)

Net loss attributable to non-controlling interest and redeemable

non-controlling interest

847

22,843

3,487

Net loss attributable to ordinary shareholders

(124,612)

(146,640)

(22,381)

Other comprehensive income (loss),net of tax of nil

Unrealized gains of available-for-sale securities

-

2,358

360

Realized gains of available-for-sale securities

-

(2,441)

(373)

Foreign currency translation adjustments

14,278

1,705

260

Comprehensive loss

(110,334)

(145,018)

(22,134)

Loss per share:

Basic and diluted

(0.76)

(0.89)

(0.14)

Loss per ADS:

Basic and diluted

(1.52)

(1.78)

(0.28)

Weighted average number of shares used in computation of loss per share

Basic and diluted

164,875

165,587,950

165,950

111,Inc.

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(In thousands)

For the three months ended March 31

2020

2021

RMB

RMB

US$

Net cash used in operating activities

(111,947)

(259,430)

(39,598)

Net cash (used in) provided by investing activities

(4,169)

85,498

13,050

Net cash used in financing activities

(64,459)

(182,820)

(27,904)

Effect of exchange rate changes on cash and cash equivalents,and

restricted cash

7,867

1,194

182

Net decrease in cash and cash equivalents,and restricted cash

(172,708)

(355,558)

(54,270)

Cash and cash equivalents,and restricted cash at the beginning of

the period

697,722

1,318,534

201,248

Cash and cash equivalents,and restricted cash at the end of the period

525,014

962,976

146,978

111,Inc.

Unaudited Reconciliation of GAAP and non-GAAP Results

(In thousands,per share and per ADS data)

For the three months ended March 31

2020

2021

RMB

RMB

US$

Loss from operations

(113,695)

(173,265)

(26,445)

Add:Share-based compensation expenses

15,200

37,377

5,705

Non-GAAP loss from operations

(98,495)

(135,888)

(20,740)

Net Loss attributable to ordinary shareholders

(124,612)

(146,640)

(22,381)

Add:Share-based compensation expenses,net of tax

15,705

Non-GAAP net Loss attributable to ordinary shareholders

(109,412)

(109,263)

(16,676)

Loss per ADS:

Basic and diluted

(1.52)

(1.78)

(0.28)

Add:Share-based compensation expenses per ADS,net of tax

0.18

0.45

0.07

Non-GAAP Loss per ADS

(1.34)

(1.33)

(0.21)

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