I-Mab Provides Updates on Status under Holding Foreign Companies Accountable Act

SHANGHAI and GAITHERSBURG,Md.,May 5,2022 -- I-Mab ("I-Mab" or the "Company") (Nasdaq: IMAB),a clinical-stage biopharmaceutical company committed to the discovery,development,and commercialization of novel biologics,today provided updates on its status under the Holding Foreign Companies Accountable Act (the "HFCAA").

The Companyis aware thatthe U.S. Securities and Exchange Commission (the "SEC")provisionallyidentifiedI-Mabasa"Commission-Identified Issuer"after the Company filed its annual report on Form 20-F for the fiscal year ended December 31,2021 with the SEC on April 29,2022,which included an audit report issuedby a public accounting firm that the Public Company Accounting Oversight Board (the "PCAOB") has determined that it is unable to inspect completely.

I-Mab understands that the SEC made such identification pursuant to the HFCAA and its implementation rules issued thereunder,which will not directly result in the delisting of the Company's American Depositary Shares("ADSs")from Nasdaq. Pursuant to the HFCAA,the SECwillprohibit a company's shares orADSsfrom being traded on a national stock exchange or in the over-the-counter trading market in the United States if the Company has been identified by the SEC for three consecutive years due to the PCAOB'sinability to inspect the registered public accounting firm's working paper related to such company.

I-Mab is in the process of engaging a selected U.S.-based independent registered public accounting firm asitsprincipal auditor that is subject to the inspection by the PCAOB. This firm also needs to comply with the applicable rules and regulations concerning information confidentiality and archives administration for compliance purposes in China.The Companyaims to completethe engagement in the second half of 2022 and subsequentchangeofits principal auditoris expected totake placeinconjunction with the filing ofitsannual report for thefiscalyear ended December 31,2022.

About I-Mab

I-Mab (Nasdaq: IMAB) is an innovation-driven global biopharma company focused on the discovery,development and commercialization of novel and highly differentiated biologics for immuno-oncology diseases. The Company's mission is to bring transformational medicines to patients around the world through innovation. I-Mab's globally competitive pipeline of more than 20 clinical and preclinical-stage drug candidates is driven by its internal discovery and global partnerships for in-licensing,based on the Company's Fast-to-Proof-of-Concept and Fast-to-Market development strategies. The Company is progressing from a clinical-stage biotech company into an innovative global specialty biopharmaceutical company with cutting-edge R&D capabilities,a world-class GMP manufacturing facility,and commercial capability. I-Mab has established its global footprint in Shanghai (headquarters),Beijing,Hangzhou,Guangzhou,Lishui and Hong Kong in China,and Maryland and San Diego in the United States. For more information,please visit http://www.i-mabbiopharma.com and follow I-Mab on LinkedIn,Twitter,and WeChat.

Forward Looking Statements

This press release includes certain disclosures which contain "forward-looking statements." You can identify forward-looking statements because they contain words such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates," and "aims." Forward-looking statements are based on I-Mab's current expectations and assumptions. Because forward-looking statements relate to the future,they are subject to inherent uncertainties,risks and changes in circumstances that may differ materially from those contemplated by the forward-looking statements,which are neither statements of historical fact nor guarantees or assurances of future performance. Important factors that could cause actual results to differ materially from those in the forward-looking statements are set forth in filings with the U.S. Securities and Exchange Commission. I-Mab undertakes no obligation to publicly update or revise any forward-looking statements,whether as a result of new information,future events or otherwise,except as may be required by law.

I-Mab Contacts

John Long

Chief Financial Officer

IR@i-mabbiopharma.com

Gigi Feng

Chief Communications Officer

PR@i-mabbiopharma.com

Investor Inquiries

The Piacente Group,Inc.

Emilie Wu

E-mail: emilie@thepiacentegroup.com

Office line: +86 21 6039 8363

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