Sirnaomics to Present Latest Developments on its GalNAc-Based Liver-Targeting Platforms and GalAhead™ Programs at the TIDES USA 2022

GAITHERSBURG,Md. and SUZHOU,China,May 11,2022 --Sirnaomics Ltd.("Sirnaomics",stock code: 2257.HK),a leading biopharmaceutical company in discovery and development of RNAi therapeutics,announced today that it will present the latest developments on its GalNAc-Liver-Targeting platforms and a progress report on its GalAhead™ technologies and programs at the TIDES USA 2022 Conference. TIDES 2022 is taking place May 9-12,2022 at the Hynes Convention Center in Boston.

Oral Presentation Details

Presentation Title: mxRNA™: Miniaturized RNAi Triggers Composed of Single Oligonucleotides

Presentation Segment: Oligonucleotide Discovery,Preclinical and Clinical

Presenter: Dmitry Samarsky,PhD,Sirnaomics Chief Technology Officer

Time/Date: 9:00am – 9:30am ET,Thursday,May 12,2022.

Location: Hynes Convention Center,Room 102

Dr. Dmitry Samarsky,Sirnaomics Chief Technology Officer,will provide an oral presentation data demonstrating mxRNA efficacy in primary hepatocytes (in vitro) and in mice (in vivo). He will also present results of a 26-week study in non-human primates conducted with the candidate molecule for Sirnaomics' frontrunner GalAhead™therapeutic program,targeting coagulation Factor XI,and report on progress made with other therapeutic programs based on the GalAhead™ platform.

For more information about Sirnaomics' presentation,visit the event website here.

About Sirnaomics

Sirnaomics is an RNA therapeutics biopharmaceutical company with product candidates in preclinical and clinical stages that focuses on the discovery and development of innovative drugs for indications with medical needs and large market opportunities. Sirnaomics is the first clinical-stage RNA therapeutics company to have a strong presence in both China and the United States,and also the first company to achieve positive Phase IIa clinical outcomes in oncology for an RNAi therapeutics for its core product,STP705. Learn more atwww.sirnaomics.com.

CONTACT:

Investors:

Nigel Yip

Chief Financial Officer,Sirnaomics

Email: NigelYip@sirnaomics.com

Media (US):

Alexis Feinberg

Tel: +1 203 939 2225

Email: Alexis.Feinberg@westwicke.com

Media (China):

Bunny Lee

Tel: +852 3150 6707

Email: sirnaomics.hk@pordahavas.com