HanAll's Second FcRn Inhibitor HL161ANS to be Added to the Development Program of its Licensed Partner

Immunovant,a HanAll's licensed partner,unveiled its plan to develop a new FcRn inhibitor,HL161ANS (also known as IMVT-1402)

In animal studies,HL161ANS indicated deep IgG reductions similar to batoclimab with no or minimal impact on albumin and LDL cholesterol level

Batoclimab (formerly known as HL161BKN) and HL161ANS originated from HanAll. Both were licensed to Roivant in 2017

SEOUL,South Korea,Oct. 4,2022 -- HanAll Biopharma (KRX: 009420.KS),a global biopharmaceutical company developing innovative medicine,clarified that the new FcRn inhibitor HL161ANS (IMVT-1402),unveiled by its licensed partner Immunovant as a new development program,is a compound discovered and developed by HanAll. Both batoclimab and HL161ANS compounds were licensed to Roivant Sciences in regions including North America,South America,and Europe in 2017. HL161ANS demonstrated deep IgG lowering similar to batoclimab with no or minimal impact on albumin and low-density lipoprotein in animal studies.

"We are excited with the potential contribution our second FcRn inhibitor HL161ANS can make to patients suffering from severe autoimmune diseases," said Sean Jeong,M.D.,CEO of HanAll Biopharma. "HL161ANS,as well as batoclimab,is another example of HanAll's advanced antibody development capability. HanAll will continue to invest globally in its R&D to deliver innovative medicines to the patients," he added.

About HanAll Biopharma Co.,Ltd.

HanAll Biopharma (KRX: 009420.KS) is a global biopharmaceutical company founded in 1973,with a mission of making meaningful contributions to patients' lives by introducing innovative,impactful therapies to address severe unmet medical needs. HanAll has been operating a portfolio of pharmaceutical products in areas ranging from endocrine,circulatory,and urologic diseases for more than 49 years.

HanAll has also expanded its focus to ophthalmology,immunology,oncology and neurology to discover and develop innovative medicines for patients with diseases for which there are no effective treatments. A leading pipeline asset,HL161BKN (INN: batoclimab),an anti-FcRn antibody drug,is in Phase 3 and Phase 2 trials across the world for the treatment of rare autoimmune disorders including myasthenia gravis,thyroid eye disease,warm autoimmune hemolytic anemia,neuromyelitis optica,and immune thrombocytopenia. Another main asset,HL036 (INN: tanfanercept),an anti-TNF alpha protein drug,is in Phase 3 clinical trials in the US and China for the treatment of dry eye disease.

For further information visit our website,and connect with us on linkedin. For any media inquiries,please contact HanAll PR/IR (pr@hanall.com,ir@hanall.com).

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