Telix 2022 Full Year Results: Revenue up 20x in first year of commercial sales, underpins transition to cash flow positive

MELBOURNE,Australia,Feb. 27,2023 -- Telix Pharmaceuticals Limited (ASX: TLX,Telix,the Company) today announces its financial results for the financial year ended 31 December 2022. All figures are in AU$ unless otherwise stated.

2022HIGHLIGHTS

Total Group revenue $160.1M (2021: $7.6M) commercial launch of Illuccix® drives 20x increase in revenue

Highly positive top-line data from Phase III ZIRCON trial of investigational kidney cancer imaging agent TLX250-CDx paves way to commence regulatory filing process for a second imaging agent for the urology field

Advancement across the core therapy pipeline programs,including:

- Patient dosing in ProstACT SELECT and TARGET prostate cancer therapy trials

- Manufacturing scale-up to facilitate commencement of the ProstACT GLOBAL trial in international sites in 2023

- Patients dosed in STARLITE-2 study of therapy candidate TLX250 in patients with advanced clear cell renal cell carcinoma (ccRCC) in combination with immunotherapy

- Final data from IPAX-1,a Phase I/II trial of TLX101,an investigational therapy in patients with recurrent glioblastoma multiforme (GBM),confirmed the study met its primary objectives and demonstrated encouraging preliminary efficacy data

Build out of the radioisotope production facility in Brussels South progressing,on-track to commence operations in 2023

Net loss after tax $104.1M (2021: $80.5M),reflecting a period of investment to scale-up commercial and clinical activities

Adjusted earnings before tax,interest,depreciation and amortisation (Adjusted EBITDA) $(67.8)M (2021: $(76.1)M)

Gross margin (62%) has steadily improved since launch,reflecting efficiency gains in manufacturing of commercial products and scale benefits

Improvement in cash balance and net cash utilisation:

- Cash and cash equivalents of $116.3M as at 31 December 2022 (2021: $22.0M)

- Improved cash balance reflects $175.0M capital raise undertaken in January 2022,cash generation from sales of Illuccix and improved operating expenditure control

- Customer receipts generated cash of $124.1M (2021: $4.2M),reflecting the commencement of commercial sales

Dr Christian Behrenbruch,Group Chief Executive Officer and Managing Director commented on the result:

"This year Telix has demonstrated it can effectively identify,develop and commercialise assets. This included the delivery of a complex Phase III trial and scale-up of the business to support the highly successful launch of our first commercial product,Illuccix. These achievements,along with a continued focus on expenditure control,have seen us finish 2022 in a strong financial position with a healthy cash balance and a growing revenue stream. Our commitment to financial stewardship is enabling us to invest our earnings to fund the late-stage programs in our pipeline,while transitioning to cash flow positive. Ultimately this will deliver further benefits to patients and shareholders.

"AlongwiththelaunchofIlluccix,thepositivereadout ofourPhaseIIIZIRCONstudyofourkidneycancerimaging agent,TLX250-CDxwasamajor highlightof2022. Welookforwardtobuildingonthisstrong foundationin2023asweprepare regulatory filings for two imaging agents for kidney and brain cancer and continue to advance the late-stage therapy programs in prostate,kidney and brain cancer."

FurtherdetailsontheCompany'sresultscanbefoundintheCompany'sAppendix4E,investorpresentationslidesand 2022 Annual Report lodged with the ASX and also available on the Company'swebsite.

InvestorCall

Aninvestorconferencecall/webcast willbeheldonTuesday 28February2023at9.00amAEDT(Monday27February 2023 at 5.00pm EST).

Participantsmayregisterforthecallatthefollowinglink: https://s1.c-conf.com/diamondpass/10028733-atfd6f.html

AboutTelixPharmaceuticalsLimited

Telix is a biopharmaceutical company focused on the development and commercialisation of diagnostic and therapeutic radiopharmaceuticals. Telix is headquartered in Melbourne,Australia with international operations in the United States,Europe(BelgiumandSwitzerland),andJapan.Telixisdevelopingaportfolioofclinical-stageproducts thataimstoaddress significant unmet medical need in oncology and rare diseases. Telix is listed on the Australian Securities Exchange (ASX: TLX).Formoreinformationvisitwww.telixpharma.comandfollow TelixonTwitter(@TelixPharma)and LinkedIn.

Telix'slead product,gallium-68 (68Ga) gozetotide (also known as 68Ga PSMA-11) injection,has been approved by the U.S.Foodand DrugAdministration (FDA),1andby theAustralianTherapeuticGoodsAdministration(TGA),2 andby HealthCanada.3

TelixInvestorRelations

Ms.Kyahn Williamson

TelixPharmaceuticalsLimited

SVPCorporateCommunicationsandInvestorRelations

Email: kyahn.williamson@telixpharma.com

ThisannouncementhasbeenauthorisedforreleasebytheTelixPharmaceuticalsLimited BoardofDirectors.

LegalNotices

This announcement is not intended as promotion or advertising directed to any healthcare professional or other audience in any country worldwide (including Australia,United States and the United Kingdom). This announcement may include forward-looking statements that relate to anticipated future events,financial performance,plans,strategies or business developments. Forward-looking statements can generally be identified by the use of words such as "may","expect","intend","plan","estimate","anticipate","outlook","forecast" and "guidance",or other similar words. Forward-looking statements involve known and unknown risks,uncertainties and other factors that may cause our actual results,levelsof activity,performance or achievements to differ materially from any future results,levels of activity,performance or achievements expressed or implied by these forward-looking statements. Forward-looking statements are based on the Company's good-faith assumptions as to the financial,market,regulatory and other risks and considerations that exist and affect the Company's business and operations in the future and there can be no assurance that any of the assumptions will prove to be correct. In the context of Telix's business,forward-looking statements may include,but are not limited to,statements about: the initiation,timing,progress and results of Telix's preclinical and clinical studies,and Telix's research and development programs; Telix's ability to advance product candidates into,enrol and successfully complete,clinical studies,including multi-national clinical trials; the timing or likelihood of regulatory filings and approvals,manufacturing activities and product marketing activities; the commercialisation of Telix's product candidates,if or when they have been approved; estimates of Telix's expenses,future revenues and capital requirements; Telix's financial performance; developments relating to Telix's competitors and industry; and the pricing and reimbursement of Telix's product candidates,if and after they have been approved. Telix's actual results,performance or achievements may be materially different from those which may be expressed or implied by such statements,and the differences may be adverse. Accordingly,you should not place undue reliance on these forward-looking statements. Readers are cautioned not to place undue reliance on forward-looking statements. Except as required by applicable laws or regulations,Telixdoes not undertake to publicly update or review any forward-looking statements. Past performance cannot be relied on asa guide to future performance. Readers should read this announcement together with our material risks,as disclosed inour most recently filed reports with the ASX and on our website.

©2023TelixPharmaceuticalsLimited. TheTelixPharmaceuticalsandIlluccixnameandlogoaretrademarksofTelix Pharmaceuticals Limited and its affiliates (all rights reserved).

1. ASX disclosure20December 2021.

2. ASXdisclosure2November2021.

3. ASXdisclosure14October2022.