SmartKem, Inc. Begins Trading on the OTCQB in the US

Seeking to reshape the world of electronics with a revolutionary new organic semiconductor platform that enables a new generation of displays,sensors and logic

MANCHESTER,England,Feb. 7,2022 --SmartKem,Inc. (the Company) announced that its common stock has commenced trading on the OTCQB Venture Marketplace ("OTCQB") in the United States under the ticker symbol "SMTK". The OTCQB is a US trading platform that is operated by the OTC Markets Group Inc. in New York.

SmartKem CEO Ian Jenks commented,"This is a huge milestone for SmartKem. Having undergone a successful private financing in February last year,we are now publicly trading on the OTCQB market,inviting investors to participate in the exciting journey in our development of next generation displays,sensors and logic."

SmartKem's OTCQB information can be found on the OTC Markets website: www.otcmarkets.com/stock/SMTK/overview

About SmartKem

SmartKem is seeking to reshape the world of electronics with a revolutionary semiconductor platform that enables a new generation of displays,sensors and logic. SmartKem's patented TRUFLEX® inks are solution deposited at a low temperature,on low-cost substrates to make organic thin-film transistor (OTFT) circuits. The company's semiconductor platform can be used in a number of applications including mini-LED displays,AMOLED displays,fingerprint sensors and integrated logic circuits. SmartKem develops its materials at its research and development facility in Manchester,UK,and its semiconductor manufacturing process at the Centre of Process Innovation (CPI) at Sedgefield,UK. The company has an extensive IP portfolio including approximately 120 issued patents.

Forward-Looking Statements

All statements in this press release that are not historical are forward-looking statements,including,among other things,statements relating to the SmartKem's expectations regarding its market position and market opportunity,expectations and plans as to its product development,manufacturing and sales,and relations with its partners and investors. These statements are not historical facts but rather are based on SmartKem Inc.'s current expectations,estimates,and projections regarding its business,operations and other similar or related factors. Words such as "may," will," "could," "would," "should," "anticipate," "predict," "potential," "continue," "expect," "intend," "plan," "project," "believe," "estimate," and other similar or elated expressions are used to identify these forward-looking statements,although not all forward-looking statements contain these words. You should not place undue reliance on forward-looking statements because they involve known and unknown risks,uncertainties,and assumptions that are difficult or impossible to predict and,in some cases,beyond the Company's control. Actual results may differ materially from those in the forward-looking statements as a result of a number of factors,including those described in the Company's filings with the Securities and Exchange Commission. The Company undertakes no obligation to revise or update information in this release to reflect events or circumstances in the future,even if new information becomes available.

www.smartkem.com