ZAP Surgical Brain Tumor Treatments Commence at PLA General Hospital 301 in Beijing, China

SAN CARLOS,California,Jan. 14,2020 --ZAP Surgical Systems,Inc. today announced that its ZAP-X® Gyroscopic Radiosurgery™ platform began clinical stereotactic radiosurgery (SRS) treatments at PLA General Hospital 301 (PLAGH 301) in Beijing,China. PLAGH 301 is the largest hospital in China with more than 20,000 outpatient treatments per day.

ZAP-X® Gyroscopic Radiosurgery™ platform

For select indications including many primary and metastatic brain tumors,SRS is proven to be an effective alternative to invasive surgery,thus potentially improving patient quality of life while significantly reducing the cost of care.

As part of a clinical study required prior to China NMPA (National Medical Products Administration) clearance,the ZAP-X will initially treat 55 patients and be assessed for overall patient safety and treatment efficacy. Having been granted CMDE's Greenpath Approval,the ZAP-X platform looks to be rapidly approved for broad clinical use following a successful clinical trial.

U.S. FDA-cleared in September of 2017,ZAP-X utilizes a modern linear accelerator to eliminate the historical use of Cobalt-60 and the related costs and challenges of handling live radioactive isotopes. ZAP-X also incorporates a unique vault-free design that typically eliminates the need for costly shielded treatment rooms.

PLA General Hospital 301 is the second center in the world to provide SRS using the ZAP-X platform. Starting in January 2019,Barrow Brain and Spine,a partner ofBarrow Neurological InstituteinPhoenix,Arizona,was the first center to offer clinical ZAP-X treatments.

"My colleagues and I are incredibly proud to be the first center in Asia to deploy this latest advance in brain tumor treatments," said Dr. Long-Sheng Pan,Associate Director of the Neurosurgery at PLAGH 301 and principal investigator (PI) for the clinical trial.

"Hospital 301 has always offered the most advanced medical technologies available. We look forward to continuing this tradition with ZAP-X," added Dr. Bao-Lin Qu,Director of Radiation Oncology at PLAGH 301.

For more about the ZAP-X Gyroscopic Radiosurgery platform,please visit: https://zapsurgical.com/. Detailed system overview animations can be found at https://youtu.be/9ph-cdb5QO0.

About ZAP Surgical Systems,Inc.

ZAP Surgical Systems,Inc. designs and manufactures the ZAP-X® radiosurgery platform. ZAP was founded in 2014 by John R. Adler,MD,Stanford Professor of Neurosurgery and founder & CEO of ZAP Surgical Systems. Dr. Adler is also the inventor of the CyberKnife® and founder of Accuray,Inc. FDA-cleared in September 2017,ZAP-X incorporates a unique self-shielded design that typically eliminates the need for traditional radiation vaults,and thus enables simple point-of-care delivery in locations previously unfeasible or cost-prohibitive,including physician offices,ambulatory surgery centers,and satellite facilities. Learn more at www.ZAPsurgical.com.

Contact:

Mark Arnold

Senior Vice President,Marketing

ZAP Surgical Systems,Inc.

Email: marka@zapsurgical.com

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