TaiGen filed US IND for its influenza antiviral TG-1000

TAIPEI,Taiwan,Oct. 5,2020 -- TaiGen Biotechnology Company,Limited ("TaiGen") announced today that it has filed an Investigational New Drug (IND) application with the US FDA for its influenza antiviral TG-1000.

TG-1000 is a novel pan-influenza antiviral,which interrupts viral replication and transmission via a cap-snatching mechanism and is able to do this effectively against influenza-A,influenza-B,avian flu H7N9,and Tamiflu-resistant viruses. The first US patent for TG-1000 was successfully prosecuted and granted by the United States Patent and Trademark Office on Jan 14th,2020.

A Phase 1 trial for in China was initiated by TaiGen in July 2020 and has successfully completed the first 4 groups in the single ascending dose part. A Phase 2 protocol has also been submitted to the institutional review board (IRB) of China-Japan Friendship Hospital in Beijing last month.

"We are excited about the IND filing in the US for the internally developed TG-1000 which has the potential to be a single dose treatment for influenza," said Kuo-Lung Huang,the Chairman and CEO of TaiGen,"TG-1000 IND filing demonstrates yet again TaiGen's capacity and experience in research and development of NCEs."

About TaiGen Biotechnology

TaiGen Biotechnology is a leading research-based and market-driven biotechnology company in Taiwan with a wholly-owned subsidiary in Beijing,China. In addition to TG-1000,TaiGen has three other in-house discovered NCEs: Taigexyn®,a novel non-fluorinated quinolone available in both oral and intravenous formulations,TG-3000,a chemokine receptor antagonist for stem cell transplantation and chemosensitization,and Furaprevir,a HCV protease inhibitor for treatment of chronic hepatitis infection. Taigexyn® is already on the market in the mainland China and Taiwan,TG-3000 has completed Phase 2 clinical studies,and Furaprevir is currently in Phase 3 clinical development.

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