Sai Life Sciences presents mid-term report on Sai Nxt initiative; reveals upsurge in capabilities

- Completes two-thirds of its investment target of US$150M

- Demonstrates a leap forward in capabilities across all focus areas – People,Processes,and Infrastructure

HYDERABAD,India,Oct. 11,2021 -- Sai Life Sciences,a leading global Contract Research,Development and Manufacturing Organisation(CRO-CDMO),today presented a midterm report on its organizational transformative initiative,Sai Nxt. Envisaged as a 4-year program from 2019 to 2023 with an investment target of US$150M,Sai Nxthas enabled a transformation in the company's capabilities across three core areas: (1) People & culture (2) Processes & automation (3) Infrastructure & scientific capabilities.

The mid-term report of Sai Life Sciences’ Sai Nxt initiative reveals a US$100M investment and significant upsurge in its capabilities

CEO & Managing Director of Sai Life Sciences,Krishna Kanumuri,said,"At the halfway mark of Sai Nxt,we have completed two-thirds of our committed investment. More importantly,it has augmented our ability to serve the needs of global pharma and biotech innovators withspeed,compliance and dependability."

En routeto excellence: Highlights from the journey so far

Guided by the insights and feedback from its innovator customers,Sai Life Sciences has expanded its R&D and manufacturing facilities,deepened scientific & technological capabilities,strengthened automation and data systems,and raised the bar for safety,quality and customer focus.

Growth in scientific depth and scale: The company's expansion into Boston and Manchester has enabled it to access some of the finest pharmaceutical talent globally and strengthened its ability to solve complex scientific challenges. The simultaneous growth in its India team has brought in niche capabilities and NCE experience.

Expansion in technology platforms and capabilities: The company has augmented its capabilities across various technologies including high-content screening (HCS),PROTACS,particle sciences & engineering,highly potent APIs,scale-up of flow processes,amidites,peptides,and more.

Fully integrated discovery and development campus,built for speed: The company has consolidated all its India R&D capabilities into a 13-acre integrated campus in Hyderabad with 1200+ scientists. The campus houses integrated discovery (chemistry,biology and DMPK/ tox),early & late phase development,comprehensive analytical capabilities,process safety,technology platforms,early phase supplies,and technology transfer.The co-location of cross-functional teams on the same site,combined with streamlined processes and automation,helps faster resolution of technical issues and improves speed.

Global delivery model for biology and process chemistry: To provide its customers an optimal solution in terms of talent,speed,and cost efficiency,the company has created specialized global R&D teams in Boston (Biology) and Manchester (Process Development) with proven ability to solve complex scientific challenges. Complementing the strong track record of handling complex projects by the India team,this allows customers the choice to begin their project in Boston or Manchester,following which projects are seamlessly tech transferred to Hyderabad for greater throughput or scale-up,as needed. This model is enabled by unified global teams supported by matching infrastructure and processes across all sites.

New state-of the-art manufacturing facilities:The company has added 172 KL API & intermediate manufacturing capacity,4 Clean rooms,at its Bidar manufacturing campus. It is on course to adding highly potent API and amidites capabilities by end-2021,additional 200 KL manufacturing capacity and a dedicated facility for companion animal health products by end-2022. With this expansion,80% of the installed capacity will be under 5 years old,and 60% under 3 years old. All new production facilities have state-of-the-art automation,data systems and safety features housed in ergonomically designed multi-purpose production blocks.

Global customer outreach: The company has expanded its business development footprintto 15 cities around the world with the aim of elevating its customer-service levels and having representation closer to customers.

Renewed thrust on Sustainability:Sai Life Sciences has made significant progress in advancing its Sustainability agenda:

‒ Became the first India-headquartered company to join the PSCI membership

‒ Joined ACS Green Chemistry Institute Pharmaceutical Roundtable (ACS-GCIPR) as an 'Associate Member'

‒ Released its first Sustainability Reportin 2020 as per GRI framework

‒ Received ISO 14001:2015 and ISO 45001:2018 certifications

‒ Became signatory of United Nations Global Compact(UNGC)

Certifications,Awards & Recognition: As a testimony to its transformation,Sai Life Sciences has won several prestigious awards and recognition across diverse categories including quality,learning & development,efficient energy practices and sustainability.

More details about Sai Nxt can be found here.

About Sai Life Sciences

Sai Life Sciences is a full-service CRO-CDMOthat works with innovator pharma and biotech companies globally,to accelerate the discovery,development and commercialisation of complex small molecules. The company has over 2200 employees across its facilities in India,UK and USA. Sai Life Sciences is privately held and backed by global investors,TPG Capital and HBM Healthcare Investments. https://www.sailife.com/

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