Frost & Sullivan Hails Sphere Fluidics for Enabling Efficient, Faster, and More Cost-effective Single-cell Analysis with Its Microfluidic Platforms

The flexible and easy-to-use microfluidic platforms easily adapt to customers' unique research needs,boost throughput and efficiency,and enhance customers' single-cell research capabilities.

SAN ANTONIO,April 11,2022 -- Frost & Sullivan recently analyzed the European microfluidic platforms for biological screening and discovery market and,based on its findings,recognizes Sphere Fluidics with the 2022 Europe Technology Innovation Leadership Award. The Company develops innovative products for single-cell analysis and characterization,and provides collaborative research and development (R&D) services. It extended this expertise to developing a technology platform that enables discovery in a range of growing markets through single-cell analysis. The platform allows faster and more cost-effective development of new biopharmaceuticals. It also improves monoclonal antibody screening,cell line development,and overall research efficiency across cell therapy,synthetic biology,single-cell diagnostics,and single-cell genome editing applications.

2022 European Microfluidic Platforms for Biological Screening and Discovery Technology Innovation Leadership Award

Sphere Fluidics' main research implementation platform includes microfluidic pumps,lasers for fluorescence assays,and biochips that generate,sort,and pick out picoliter volume droplets (picodroplets). Its picodroplet incubation technology empowers ultra-sensitive,rapid miniaturized assays of target proteins secreted from tens of millions of individual cells. The novel method stabilizes picodroplets and their cellular and molecular content across various conditions,facilitating high-throughput screening—a primary technical attribute. Liquid picodroplets generated at high speed encapsulate individual cells (up to 40 million),enabling the screening and analysis of cells and their secreted molecules. The picodroplet single cell encapsulation and assay systems generate,isolate,and dispense picodroplets for various applications.

"The revolutionary,high-throughput single-cell analysis platform enables fast,cost-effective biologics discovery and development and improves monoclonal antibody screening,and overall research efficiency. The flexible and easy-to-use microfluidic platforms effortlessly adapt to customers' unique research needs,enhance customers' single-cell research capabilities,and improve their chances of finding highly valuable and rare biological variants among vast cell populations," explained Aarthi Janakiraman,an industry analyst.

Sphere Fluidics' Cyto-Mine® single-cell analysis system is the first integrated benchtop platform to automatically analyze,and dispense millions of individual cells. It uniquely screens between 200,000 and 40,000,000 cells simultaneously,and can process millions of samples per day. Its automated isolation,selective screening,sorting,imaging,and clone verification streamline workflows and enable high-value clone capture in a single run,reducing costs and accelerating research. The Cyto-Mine® system's high throughput distinguishes it from other competing offerings,supporting relevant research fields marked by solid growth. The platform is a one-stop-shop for antibody discovery and stable cell-line generation for B cell type,hybridoma,Chinese hamster ovary (CHO),and human embryonic kidney (HEK) cells.

"Sphere Fluidics is well-positioned to capture growth opportunities in the market,with an industry-leading product that provides tremendous value in high-demand research sectors," said Janakiraman.

Sphere Fluidics adopts a customer-led strategy to bring best-in-class products and solutions consistently to market that provide tremendous value in high-demand research sectors. It understands clients' distinctive needs and emerging demands,and it takes steps to develop the most up-to-date and advanced single-cell analysis and monoclonality assurance systems. These enable leading-edge research and accelerate biotherapeutics discovery. With its strong overall performance,it earns the 2022 Frost & Sullivan Technology Innovation Leadership Award in the microfluidic platforms for the biological screening and discovery industry.

Each year,Frost & Sullivan presents this award to the company that has developed a product with innovative features and functionality that is gaining rapid acceptance in the market. The award recognizes the quality of the solution and the customer value enhancements it enables.

Frost & Sullivan Best Practices awards recognize companies in various regional and global markets for demonstrating outstanding achievement and superior performance in leadership,technological innovation,customer service,and strategic product development. Industry analystscompare market participants and measure performance through in-depth interviews,analyses,and extensive secondary research to identify best practices in the industry.

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Contact:

Claudia Toscano

P: 1.956.533.5915

E: claudia.toscano@frost.com

About Sphere Fluidics www.spherefluidics.com

Sphere Fluidics develops and manufactures single cell analysis and monoclonality assurance systems to enable leading edge research and accelerate biotherapeutic discovery and development.

The Company's picodroplet incubation technology enables ultra-sensitive,rapid miniaturized assays of target proteins secreted from tens of millions of individual cells.

Sphere Fluidics' Cyto-Mine® System integrates isolation,and clone verification into a single automated platform to streamline workflows,reduce costs,improve throughput and enable high-value clones to be captured in a single run.

Sphere Fluidics is located in Babraham Research Campus and Granta Park in Cambridgeshire (UK). The Company has also internationalized its business via a global network of distributors.

Follow Sphere Fluidics on Twitter @SphereFluidicsand LinkedIn @Sphere Fluidics Limited.

Contact:

Sphere Fluidics

Dr. Frank F. Craig

Tel: +44 (0)7805 659566

Email: frank.craig@spherefluidics.com

Zyme Communications

Lily Jeffery

Tel: +44 (0)7891 477 378

Email: lily.jeffery@zymecommunications.com