Advanced Instruments Introduces Solentim VIPS™ PRO, A High Efficiency Single Cell Seeder to Optimize Cell Line Development Workflows

VIPS PRO delivers powerful and efficient seeding technology and definitive proof of monoclonality for workflow productivity and confidence.

NORWOOD,Mass.,Sept. 28,2022 --Advanced Instruments today announced the launch of Solentim VIPS PRO,a high efficiency single cell seeder,at the BioProcess International Conference in Boston,Massachusetts. VIPS PRO revolutionizes cell line development (CLD) and GMP manufacturing by combining powerful seeding technology with two-step,image-based proof of monoclonality and proprietary Artificial Intelligence-driven cell recognition for increased productivity and confidence.

Solentim VIPS™ PRO Single Cell Seeder from Advanced InstrumentsHigh efficiency,single cell seeding with image-based proof of clonality for GMP-compatible workflows

A major challenge in CLD is providing absolute proof of clonal line generation that regulatory authorities require. VIPS PRO offers a unique Double-Lock Assurance of clonality,generating the two pieces of image-based evidence required for IND submission. Compared to other methods,such as limiting dilution,VIPS PRO's industry-leading seeding and clonal assurance process eliminates human error,reduces hands-on time,and accelerates process development and clinical manufacturing.

Based on the original VIPS technology,VIPS PRO is an indispensable technology for bringing innovative biotherapeutics to market. The instrument delivers a of range benefits for GMP-compatible clinical manufacturing labs,including:

Highly efficient,automated single cell seeding

Two-step,image-based Double-Lock Assurance of clonality

Intelligent cell detection

Single-use,GMP-friendly consumables

Advanced data management and analysis with the STUDIUS™ software platform

GMP-compatible workflow,including security features that support 21 CFR Part 11 compliance

Ergonomic instrument design with easy-to-access components

"VIPS PRO is a game-changer for single cell seeding,combining powerful,efficient seeding technology withdefinitive image-based proof—NOT probability—of monoclonality," said Byron Selman,CEO of Advanced Instruments. "At Advanced Instruments,customer feedback is integral to what we do and how we design new products. VIPS PRO builds on our trusted VIPS technology with thoughtful updates that meet the needs of our customers."

VIPS PRO is part of an ecosystem of technologies from Advanced Instruments built to accelerate cell line development workflows,from initial discovery to scale-up and manufacturing of biotherapeutics. To learn more about VIPS PRO,visit https://www.aicompanies.com/single-cell-seeder/vips-pro/

For Further Information:

Contact: Lisa Fahey,VP Global Marketing

lfahey@aicompanies.com

About Advanced Instruments

Advanced Instruments is a global provider of scientific and analytical instruments for the bioprocessing and clinical industries. For more than 65 years,the company's innovations have helped organizations improve quality of results,achieve reliable outcomes,and increase workplace productivity. In the biopharma space,the Solentim portfolio of best-in-class imaging and single-cell deposition technologies enables the clonal isolation,outgrowth,and characterization of the highest value cells for monoclonal antibody upstream development and cell and gene therapy. Its OsmoTECH®line of micro-osmometers are built specifically to support workflows throughout every phase of bioprocessing. Similarly,clinical labs worldwide rely on Advanced Instruments' innovative solutions for delivery of accurate and timely patient results in their clinical chemistry,microbiology,and hematology labs. For more information,visit www.aicompanies.com