Mundipharma to Provide Access to Breakthrough Cold-Fighting Product for Adults and Children in the Middle East and Africa

BETADINE™ Cold Defence Nasal Spray is a natural product with anti-viral effects that helps to eliminate 99% of cold and flu viruses and shorten the duration of common colds.

First launched in Asia in 2017,the over-the-counter treatment is already available in more than 14 countries as part of Mundipharma's BETADINE™range of consumer healthcare products.

SINGAPORE,Jan. 22,2019 -- Mundipharma will be introducing BETADINE™ Cold Defence,a new early treatment hailed as a "world-first"[i],in the Middle East and Africa to help families stay healthy and fight the common cold.

Professor Ronald Eccles,who established the Common Cold Centre at Cardiff University in 1988 and has been involved in over 120 clinical trials for over 30 years,said: "This is one of the most exciting developments I've ever seen," and described it as "safe and effective".[ii]

Common cold and flu-like illnesses are viral infections that affect adults twice per year on average. The impact is greater for children who can typically contract them up to five to seven times per year due to their close proximity at school and play.

Clinical trials have showed that BETADINE™ Cold Defencereduced duration of the disease by up to two days for children and by two days for adults,increased viral clearance and reduced severity of cold and flu-like symptoms.[iii],[iv]

BETADINE™ Cold Defence is a natural product with anti-viral effects that helps reduce duration of colds in adults and children. It is delivered as a nasal spray and contains the ingredient iota-carrageenan,also called Carragelose®. It is available in adult and children's formulations and is recommended for use at the first sign of cold and flu-like symptoms.

Several large scale clinical trials involving close to 600 adult and paediatric patients were conducted to evaluate the efficacy and safety of the product. The analysis of children and adults suffering from virus-confirmed common cold after two randomized,double-blind,placebo-controlled trials demonstrated that it appeared as an effective treatment of common cold[v],[iv],[vi]

Mundipharma CEO,Raman Singh,said: "Every year the common cold interrupts family,school and working life,soaking up medical leave,putting pressure on productivity and colleagues and interrupting people's daily life. As an early treatment to manage cold and other flu-like illnesses,BETADINE™ Cold Defence can help keep families and workplaces productive and healthy.

"ProvidingBETADINE™ Cold Defence in the Middle East and Afr ica continues our commitment to the day-to-day wellbeing of people of all ages."

[i]

Interview about Cold Defence nasal spray with Professor Ron Eccles,Weekend Sunrise,ChannelSeven Melbourne,Sunday 6th May at 8.18AM

[ii]

Interview about Cold Defence nasal spray with Professor Ron Eccles,Sunday 6th May at 8.18AM

[iii]

Ludwig et al. Efficacy of carrageenan nasal spray in patients with common cold: a randomized controlled trial. Respiratory Research 2013;14:124.

[iv]

Lessons learned from a double-blind randomised placebo-controlled study with an iota-carrageenan nasal spray as medical device in children with acute symptoms of common cold',Tamas Fazekas,Philipp Eickhoff,Nathalie Pruckner,Georg Vollnhofer,Gustav Fischmeister,Christopher Diakos,Margit Rauch,Maria Verdianz,Andreas Zoubek,Helmut Gadner and Thomas Lion,BMC Complementary and Alternative Medicine,The official journal of the International Society for Complementary Medicine. Published,5 September 2012.

[v]

'Lessons learned from a double-blind randomised placebo-controlled study with an iota-carrageenan nasal spray as medical device in children with acute symptoms of common cold',5 September 2012.

[vi]

Koenighofer,M.,et al. Carrageenan nasal spray in virus confirmed common old: individual patient data analysis of two randomized controlled trials. Multidisciplinary Respiratory Medicine. 2014;9:57.

About Mundipharma

Mundipharma is a network of independent associated companies,which are privately owned entities,covering pharmaceutical markets in Asia-Pacific,Latin America,the Middle East and Africa. The headquarters for these territories is in Singapore. Mundipharma consistently delivers high-quality medicines while standing by the values it represents. Its mission is to alleviate the suffering of patients and to substantially improve their quality of life. Mundipharma is dedicated to bringing to patients the benefit of novel treatment options in fields such as pain,oncology,oncology supportive care,ophthalmology,respiratory disease and consumer healthcare.

For more information please visit:www.mundipharma.com.sg

®: BETADINE is a Registered Trademark of Mundipharma; Carregelose is a Registered Trademark of Marinomed.

™: BETADINE Cold Defence is a Trademark of Mundipharma in the Middle East and Africa.

Registered indications differ country to country hence please check with a local Mundipharma office for more information on the local approved prescribing information.

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